Inspired by the work of Prof Christopher Gillberg and his colleagues, and the work of Drs Judith Gould and Lorna Wing, the origins of the Neurodiversity Centre were in clinical work being done over the last 13 years with families and individuals presenting with neurodevelopmental challenges or differences. The organisation was formally established in 2016, as a dynamic, learning and service-user-oriented organisation committed to offering comprehensive support, understanding and inclusion for those with neurodevelopmental challenges or differences affecting their daily lives. Headquartered in the Western Cape of South Africa, the Neurodiversity Centre operates eight branches and collaborates with satellite-licensed associated branches (LABS) in KwaZulu-Natal, extending our services nationwide and internationally. With a robust multidisciplinary team of approximately 80 dedicated professionals, we aim to serve as a global ESSENCE hub serving, supporting, and including the communities in which we work in our clinical, research and training programmes.